At its December 2007 Executive Board meeting, America In Solidarity established its key issues to concentrate in 2008. They include:
- Holding corporations accountable toward workers, the environment and local communities
- The elimination of war profiteering while encouraging government support for veterans, including adequate health care for them and their families
- Withdrawal from the World Trade Organization and free trade agreements such as NAFTA and CAFTA
- Establishing a national single payer system for health care
- Increasing living wages and safe working conditions for American families
- Campaign finance reform including clean elections, paper trails at the polls and instant runoff voting

